Activating mutations in the epidermal growth factor receptor underlying responsiveness of non–small-cell lung cancer to gefitinib

TJ Lynch, DW Bell, R Sordella…

Index: Yoneda, Norihiko; Fukuhara, Tsuyoshi; Kikuchi, Tetsuo; Suzuki, Akira Synthetic Communications, 1989 , vol. 19, # 5and6 p. 865 - 872

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Citation Number: 9479

Abstract

... is responsible for the Dark Skin (dsk5) trait, associated with altered EGFR signaling.19 A fourth ... Matched normal tissue was available for Patients 1, 4, 5, and 6 and showed only the wild-type ... with non–small-cell lung cancer who had had no response to gefitinib (P<0.001 by a two ...