Process Development for Scale-Up of a Novel 3, 5-Substituted Thiazolidine-2, 4-dione Compound as a Potent Inhibitor for Estrogen-Related Receptor 1

X Li, RK Russell, J Spink, S Ballentine…

Index: Shaw, Simon J.; Goff, Dane A.; Boralsky, Luke A.; Irving, Mark; Singh, Rajinder Journal of Organic Chemistry, 2013 , vol. 78, # 17 p. 8892 - 8897

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Citation Number: 5

Abstract

... Select a Journal or Book ... Organic Process Research ... By working together with medicinal chemistry, our goals for the 50-g campaign of 26 were: (1) to quickly develop a N 1 -selective and scalable process for intermediate aldehyde 5, (2) to discover a nonmicrowave epoxide ...