Abstract A new continuous-flow system for C [BOND] H borylation has been developed. An insoluble catalyst prepared from chloro (1, 5-cyclooctadien) iridium (I) dimer and 2, 2′- bipyridine-4, 4′-dicarboxylic acid in the presence of bis (pinacolato) diboron exhibited high reactivity under continuous-flow processing without the loss of expensive iridium metal.
[Boller, Timothy M.; Murphy, Jaclyn M.; Hapke, Marko; Ishiyama, Tatsuo; Miyaura, Norio; Hartwig, John F. Journal of the American Chemical Society, 2005 , vol. 127, # 41 p. 14263 - 14278]
![2-Benzo[b]Thiophene-2-Boronic Acid Pinacol Ester Structure](https://image.chemsrc.com/caspic/300/376584-76-8.png)