Tetrahedron letters

A new synthesis of the anti-AIDS drug AZT from 5-methyluridine

BC Chen, SL Quinlan, JG Reid

Index: Chen, Bang-Chi; Quinlan, Sandra L.; Reid, J. Gregory Tetrahedron Letters, 1995 , vol. 36, # 44 p. 7961 - 7964

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Citation Number: 13

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The anti-AIDS drug AZT is prepared in six steps in 44% overall yield starting from the readily available ribonucleoside 5-methyluridine. ... 1 H-NMR data for compound3 (DMSO-d 6 ) δ 1.57 (s, 3H), 2.55 (m, 2H), 3.32 (s, 3H), 4.45 (s, 1H), 4.48–4.60 (m, 2H), 5.47 (m, 1H), 6.22 (t, ...