Tetrahedron

Synthesis of dinucleotides containing a bridged non-chiral internucleotide 5′-or 3′-phosphoramidate linkage

M Mag, JW Engels

Index: Mag, Matthias; Engels, Joachim W. Tetrahedron, 1994 , vol. 50, # 34 p. 10225 - 10234

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Citation Number: 14

Abstract

The synthesis of several dinucleoside phosphate derivatives which are linked by phosphoramidate bonds [3′-OP ( O)(O−)-NH-5′ or 3′-NH-P ( O)(O−)-O-5′] has been accomplished. The internucleoside phosphoramidate linkage was performed using the