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e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Total synthesis of papulacandin D

SE Denmark, CS Regens…

Index: Gioeli, Carlo; Balgobin, Neil; Josephson, Staffan; Chattopahyaya, Jyoti B. Tetrahedron Letters, 1981 , vol. 22, p. 969 - 972

Full Text: HTML

Citation Number: 103

Abstract

... Volume: Page: Digital Object Identifier (DOI). ... FEBS Letters (1981), 129 (2), 249-52CODEN: FEBLAL ; ISSN:0014-5793. Papulacandin B and aculeacin A inhibited β-1,3-glucan synthase (I) activity in cell-free exts. of G. lactis and addn. ...

 Related Synthetic Route
2-nitroethyl (2-(trimethylsilyl)ethyl) carbonate Structure

78687-51-1

2-nitroethyl (2...

~91%

2-Nitroethanol Structure

625-48-9

2-Nitroethanol

ethene Structure

54509-73-8

ethene

Fluoro(trimethyl)silane Structure

420-56-4

Fluoro(trimethy...

((2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl (2-(trimethylsilyl)ethyl) carbonate Structure

78687-52-2

((2R,3S,5R)-3-h...

~94%

ethene Structure

54509-73-8

ethene

Fluoro(trimethyl)silane Structure

420-56-4

Fluoro(trimethy...

Thymidine Structure

50-89-5

Thymidine

2-nitroethyl (2-(trimethylsilyl)ethyl) carbonate Structure

78687-51-1

2-nitroethyl (2...

~0%

2-Nitroethanol Structure

625-48-9

2-Nitroethanol

ethene Structure

54509-73-8

ethene

Fluoro(trimethyl)silane Structure

420-56-4

Fluoro(trimethy...

3-nitrophenyl (2-(trimethylsilyl)ethyl) carbonate Structure

78687-53-3

3-nitrophenyl (...

~0%

ethene Structure

54509-73-8

ethene

Fluoro(trimethyl)silane Structure

420-56-4

Fluoro(trimethy...

3-Nitrophenol Structure

554-84-7

3-Nitrophenol

(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl (2-(trimethylsilyl)ethyl) carbonate Structure

78687-54-4

(2,3-dihydroben...

~0%

ethene Structure

54509-73-8

ethene

Fluoro(trimethyl)silane Structure

420-56-4

Fluoro(trimethy...

2,3-Dihydro-1,4-benzodioxin-2-ylmethanol Structure

3663-82-9

2,3-Dihydro-1,4...

((2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl (2-(trimethylsilyl)ethyl) carbonate Structure

78687-52-2

((2R,3S,5R)-3-h...

~0%

ethene Structure

54509-73-8

ethene

Fluoro(trimethyl)silane Structure

420-56-4

Fluoro(trimethy...

Thymidine Structure

50-89-5

Thymidine

(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl (2-(trimethylsilyl)ethyl) carbonate Structure

78687-50-0

(3S,8S,9S,10R,1...

~0%

ethene Structure

54509-73-8

ethene

Fluoro(trimethyl)silane Structure

420-56-4

Fluoro(trimethy...

cholesterol Structure

57-88-5

cholesterol

(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl (2-(trimethylsilyl)ethyl) carbonate Structure

78687-50-0

(3S,8S,9S,10R,1...

~91%

ethene Structure

54509-73-8

ethene

Fluoro(trimethyl)silane Structure

420-56-4

Fluoro(trimethy...

cholesterol Structure

57-88-5

cholesterol

3-nitrophenyl (2-(trimethylsilyl)ethyl) carbonate Structure

78687-53-3

3-nitrophenyl (...

~90%

ethene Structure

54509-73-8

ethene

Fluoro(trimethyl)silane Structure

420-56-4

Fluoro(trimethy...

3-Nitrophenol Structure

554-84-7

3-Nitrophenol

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Detail Synthetic Route


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