A synthesis of human proinsulin C-peptide.

K Igano, Y Minotani, N Yoshida, M Kono…

Index: Igano; Minotani; Yoshida; et al. Bulletin of the Chemical Society of Japan, 1981 , vol. 54, # 10 p. 3088 - 3094

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Citation Number: 4

Abstract

A peptide corresponding to the thirty-one amino acid sequence of human proinsulin C- peptide (positions 33–63 of proinsulin) was synthesized by the solid-phase method. The product was purified consecutively by gel filtration, DEAE-cellulose chromatography, and high-performance liquid chromatography (HPLC). The purified material behaved as a single component in reversed-phase HPLC, gave correct amino acid ratios, and was not ...

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