Regioselective hydration of alkynes by iron (III) Lewis/Brønsted catalysis

JR Cabrero??Antonino, A Leyva??Pérez…

Index: Cabrero-Antonino, Jose R.; Leyva-Perez, Antonio; Corma, Avelino Chemistry - A European Journal, 2012 , vol. 18, # 35 p. 11107 - 11114

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Citation Number: 44

Abstract

Abstract The triflimide iron (III) salt [Fe (NTf 2) 3] promotes the direct hydration of terminal and internal alkynes with very good Markovnikov regioselectivities and high yields. The enhanced carbophilic Lewis acidity of the Fe III cation mediated by the weakly-coordinating triflimide anion is crucial for the catalytic activity. The iron (III) metal salt can be recycled in the form of the OPPh 3/[Fe (NTf 2) 3] system with similar activity and selectivity. However, ...