Synthesis and SAR of indazole-pyridine based protein kinase B/Akt inhibitors

KW Woods, JP Fischer, A Claiborne, T Li…

Index: Bioorganic and Medicinal Chemistry, , vol. 14, # 20 p. 6832 - 6846

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Citation Number: 62

Abstract

... JavaScript is disabled on your browser. Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry. Volume 14, Issue 20, 15 October 2006, Pages 6832–6846. Cover image Cover image. ... 22. 2. Chemical synthesis. Compound 1 (Fig. ...

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methyl indazolyl-3-carboxylate Structure

43120-28-1

methyl indazoly...

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Methyl 5-iodo-1H-indazole-3-carboxylate Structure

1079-47-6

Methyl 5-iodo-1...

Indazole-3-carboxylic acid Structure

4498-67-3

Indazole-3-carb...

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Methyl 5-iodo-1H-indazole-3-carboxylate Structure

1079-47-6

Methyl 5-iodo-1...

5-Bromo-2-fluorobenzaldehyde Structure

93777-26-5

5-Bromo-2-fluor...

~%

5-Bromo-3-ethyl-1H-indazole Structure

864774-67-4

5-Bromo-3-ethyl...

5-Bromo-2-fluorobenzaldehyde Structure

93777-26-5

5-Bromo-2-fluor...

~%

1-(5-Bromo-2-fluorophenyl)ethanone Structure

198477-89-3

1-(5-Bromo-2-fl...

5-Bromo-2-fluorobenzaldehyde Structure

93777-26-5

5-Bromo-2-fluor...

~%

1-(5-bromo-2-fluorophenyl)propan-1-one Structure

864774-65-2

1-(5-bromo-2-fl...

1-(2-Amino-5-bromophenyl)ethanone Structure

29124-56-9

1-(2-Amino-5-br...

~%

6-bromo-4-chlorocinnoline Structure

68211-15-4

6-bromo-4-chlor...

N-(2-acetyl-4-bromophenyl)acetamide Structure

29124-64-9

N-(2-acetyl-4-b...

~%

6-bromo-4-chlorocinnoline Structure

68211-15-4

6-bromo-4-chlor...

2'-Aminoacetophenone Structure

551-93-9

2'-Aminoacetophenone

~%

6-bromo-4-chlorocinnoline Structure

68211-15-4

6-bromo-4-chlor...

Acetanilide, 2-acetyl- Structure

5234-26-4

Acetanilide, 2-...

~%

6-bromo-4-chlorocinnoline Structure

68211-15-4

6-bromo-4-chlor...

1-(5-Bromo-2-fluorophenyl)ethanol Structure

552331-15-4

1-(5-Bromo-2-fl...

~%

5-Bromo-3-methyl-1H-indazole Structure

552331-16-5

5-Bromo-3-methy...

5-Bromo-2-fluorobenzaldehyde Structure

93777-26-5

5-Bromo-2-fluor...

~%

5-Bromo-3-methyl-1H-indazole Structure

552331-16-5

5-Bromo-3-methy...

6-bromo-4-chlorocinnoline Structure

68211-15-4

6-bromo-4-chlor...

~%

6-Bromocinnoline Structure

318276-72-1

6-Bromocinnoline

6-BroMocinnolin-4-ol Structure

876-88-0

6-BroMocinnolin-4-ol

~%

6-Bromocinnoline Structure

318276-72-1

6-Bromocinnoline

1-(2-Amino-5-bromophenyl)ethanone Structure

29124-56-9

1-(2-Amino-5-br...

~%

6-Bromocinnoline Structure

318276-72-1

6-Bromocinnoline

N-(2-acetyl-4-bromophenyl)acetamide Structure

29124-64-9

N-(2-acetyl-4-b...

~%

6-Bromocinnoline Structure

318276-72-1

6-Bromocinnoline

2'-Aminoacetophenone Structure

551-93-9

2'-Aminoacetophenone

~%

6-Bromocinnoline Structure

318276-72-1

6-Bromocinnoline

Acetanilide, 2-acetyl- Structure

5234-26-4

Acetanilide, 2-...

~%

6-Bromocinnoline Structure

318276-72-1

6-Bromocinnoline


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