Journal of the American Oil Chemists' Society

Selection of alcohols through Plackett-Burman design in lipase-catalyzed synthesis of anthranilic acid esters

CVS Babu, S Divakar

Index: Babu, C. V. Suresh; Divakar, S. Journal of the American Oil Chemists' Society, 2001 , vol. 78, # 1 p. 49 - 52

Full Text: HTML

Citation Number: 12

Abstract

Abstract Lipase-catalyzed synthesis of esters of anthranilic acid was attempted by employing alcohols of carbon chainlength C 1–C 18 using Plackett-Burman experimental design. Of the alcohols employed, methanol, decanol, cetyl alcohol, and stearyl alcohols showed 99.9% significance. Esterification of anthranilic acid with methanol gave the highest yield at 45.6%. This study allows the selection of better alcohols for esterification of anthranilic acid.