Approach to the library of fused pyridine-4-carboxylic acids by Combes-type reaction of acyl pyruvates and electron-rich amino heterocycles

DM Volochnyuk, SV Ryabukhin…

Index: Journal of Combinatorial Chemistry, , vol. 12, # 4 p. 510 - 517

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Citation Number: 11

Abstract

... Journal of Combinatorial ... been considered as a mainstream approach to drug discovery and lead optimization in the combinatorial chemistry over the ... libraries of compounds derived from heterocyclic scaffolds, which undeniably dominate in medicinal chemistry.(2) Derivatives of ...