2-(Trimethylsilyl) ethanol as a new alcohol equivalent for copper-catalyzed coupling of aryl iodides

M Dibakar, A Prakash, K Selvakumar, K Ruckmani…

Index: Dibakar, Mullick; Prakash, Anjanappa; Selvakumar, Kumaravel; Ruckmani, Kandasamy; Sivakumar, Manickam Tetrahedron Letters, 2011 , vol. 52, # 41 p. 5338 - 5341

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Citation Number: 5

Abstract

Aryl ethers and phenols are very important structural motifs of numerous biologically active natural products and important pharmaceutical compounds and polymers in the material science industries and consequently, much research has been focused on their synthesis. 1, 2 and 3 Available methods for the synthesis of aryl ethers and phenols via direct nucleophilic or Cu(I)-catalyzed substitution of an aryl halide with an alcohol typically require high reaction temperatures ...