On the Role of Nitrogen Monoxide (Nitric Oxide) in the Nitration of a Tyrosine Derivative and Model Compounds

E Giorgini, R Petrucci, P Astolfi…

Index: Giorgini, Elisabetta; Petrucci, Rita; Astolfi, Paola; Mason, Ronald P.; Greci, Lucedio European Journal of Organic Chemistry, 2002 , # 23 p. 4011 - 4017

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Citation Number: 4

Abstract

Abstract The nitration of tyrosine derivatives with nitrogen monoxide (nitric oxide) occurs only in the presence of dioxygen, and the hypothesized mechanism involves nitrogen dioxide (· NO 2). For better understanding of the reaction mechanism, the nitration of model compounds− such as 1-and 2-naphthols and their corresponding 2-and 1-nitroso derivatives− with nitrogen monoxide in the presence and in the absence of dioxygen was ...