A Benzopyrane Derivative as a P??Glycoprotein Stimulator: A Potential Agent to Decrease β??Amyloid Accumulation in Alzheimer's Disease

…, C Inglese, F Berardi, M Leopoldo, R Perrone…

Index: Contino, Marialessandra; Cantore, Mariangela; Capparelli, Elena; Perrone, Maria Grazia; Niso, Mauro; Inglese, Carmela; Berardi, Francesco; Leopoldo, Marcello; Perrone, Roberto; Colabufo, Nicola Antonio ChemMedChem, 2012 , vol. 7, # 3 p. 391 - 395

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Citation Number: 12

Abstract

Neurodegenerative disorders such as Alzheimer's disease (AD) are characterized by slow and progressive loss of one or more functions of the central nervous system (CNS). Since many factors, often little-known, are involved in the pathogenesis of these diseases, and their diagnosis is related to the clinical symptoms, AD is usually diagnosed in an advanced stage precluding the possibility of an effective disease-modifying agent rather than a ...