Synthesis of hydroxyderivatives of 4-methylcoumarin

SI Zav'yalov, OV Dorofeeva, EE Rumyantseva…

Index: Zav'yalov; Dorofeeva; Rumyantseva; Zavozin Pharmaceutical Chemistry Journal, 1996 , vol. 30, # 3 p. 204 - 205

Full Text: HTML

Citation Number: 1

Abstract

Coumarin V and some other hydroxyderivatives of 4-methylcoumarin are usually obtained by the Pechman reaction, involving polycondensation of two-and three-atomic phenols with acetoacetic ester (AE) in the presence of H2SO4 [I, 5]. A disadvantage of this method is the comparatively low and unstable yield of the target coumarins V and VIII. In this work we propose new efficient two-and threecomponent systems for for the Pechman reaction with ...