Low??Pressure Hydrogenation of Arenecarboxylic Acids to Aryl Aldehydes

LJ Goossen, BA Khan, T Fett…

Index: Goossen, Lukas J.; Khan, Bilal Ahmad; Fett, Thomas; Treu, Matthias Advanced Synthesis and Catalysis, 2010 , vol. 352, # 13 p. 2166 - 2170

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Citation Number: 18

Abstract

Abstract A highly effective palladium catalyst has been developed that allows the selective hydrogenation of arenecarboxylic acids to the aryl aldehydes in the presence of pivalic anhydride already at 5 bar hydrogen pressure. With the new catalyst, diversely functionalized aromatic and heteroaromatic aldehydes are conveniently accessible from the corresponding carboxylic acids in a single reaction step without any overreduction to the ...