Tetrahedron letters

Mild and convenient oxidation of aromatic heterocyclic primary alcohols by 4-acetylamino-2, 2, 6, 6-tetramethylpiperidine-1-oxoammonium perchlorate

CA Kernag, JM Bobbitt, DV McGrath

Index: Kernag, Casey A.; Bobbitt, James M.; McGrath, Dominic V. Tetrahedron Letters, 1999 , vol. 40, # 9 p. 1635 - 1636

Full Text: HTML

Citation Number: 26

Abstract

Hydroxymethyl substituted aromatic heterocycles, including pyridines, furans, and thiophenes, are oxidized to the corresponding aldehydes in excellent yields by 4- acetylamino-2, 2, 6, 6-tetramethylpiperidine-1-oxoammonium perchlorate (1) with minimal workup.