Synthesis and biological evaluation of ATP analogues acting at putative purinergic P 2X-receptors (on the guinea pig bladder)

W Howson, EM Taylor, ME Parsons, R Novelli…

Index: Howson, William; Taylor, Edwin Michael; Parsons, Michael Edward; Novelli, Riccardo; Wilczynska, Maria Aleksandra; Harris, Deborah Tracy European Journal of Medicinal Chemistry, 1988 , vol. 23, p. 433 - 440

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Citation Number: 19

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... This paper describes studies carried out on a series of ATP analogues on the guinea pig bladder, a tissue reported to possess purinergic P 2X -receptors. ... Optimisation of the pharmacological experimental technique enabled reproducible responses to ATP to be obtained in the 0.2– ...