Tetrahedron

Configurational studies on 2-[∝-(2-ethoxyphenoxy) benzyl] morpholine fce 20124

P Melloni, A Della Torre, E Lazzari, G Mazzini…

Index: Melloni; Della Torre; Lazzari; et al. Tetrahedron, 1985 ,  vol. 41,  # 7  p. 1393 - 1399

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Citation Number: 63

Abstract

The relative configuration of the two diastereoisomers of (±) 2-[∢-(2-ethoxyphenoxy) benzyl] morpholine is determined by a synthesis involving regio and stereo specific reactions.(RS, RS) diastereoisomer FCE 20124 was separated into its (+) and (-) enantiomers both by crystallization of the optically active mandelate salt and by a multi-step synthesis from (+)- (2S, 3R)-3-phenylglycidic acid.