Chemistry letters

PEG-mediated Facile Protocol for N-Boc Protection of Amines

V Siddaiah, GM Basha, GP Rao, UV Prasad, RS Rao

Index: Siddaiah; Basha; Padma Rao; Viplava Prasad; Suryachendra Rao Chemistry Letters, 2010 , vol. 39, # 11 p. 1127 - 1129

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Citation Number: 4

Abstract

We have reported an efficient and eco-friendly protocol for the protection of various structurally and electronically divergent aryl and aliphatic amines using (Boc) 2 O in the presence of PEG-400 at room temperature. The reaction gave excellent yields with low as well as high molecular weight PEGs.