Synthetic Communications®

A Novel and Efficient Reaction of Imidazolidin-2-one and N-Acylbenzotriazoles: A Facile Synthesis of 1-Acylimidazolidin-2-one

J Li, Y Sun, Z Chen, W Su

Index: Li, Jianjun; Sun, Yan; Chen, Zhiwei; Su, Weike Synthetic Communications, 2010 , vol. 40, # 24 p. 3669 - 3677

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Citation Number: 3

Abstract

Acylation of imidazolidin-2-one with readily available N-acylbenzotriazoles, in the presence of K2CO3, produced 1-acylimidazolidin-2-ones and N, N′-diacyl-imidazolidin-2-one in moderate to good yields. The utilization of N-acylbenzotriazoles which make the reaction simple and mild, may be especially advantageous when the corresponding acid chlorides are not stable or not easily prepared. It's also an example of the reaction of N- ...