Catalytic application of a Ru-alkylidene in the nucleophilic addition of several carboxylic acids on terminal alkynes and the homo-coupling of 1-alkynes

K Melis, D De Vos, P Jacobs, F Verpoort

Index: Melis, Karen; De Vos, Dirk; Jacobs, Pierre; Verpoort, Francis Journal of Organometallic Chemistry, 2003 , vol. 671, # 1-2 p. 131 - 136

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Citation Number: 36

Abstract

Thermal treatment of Ru-alkylidene (4) bearing a triazol-5-ylidene (NHC) ligand (2) at 110° C and addition of a terminal alkyne generates a ruthenium vinylidene. The thermolysed Ru- alkylidene catalyses the vinylation and dimerisation of 1-alkynes. The nucleophilic addition of acetic acid on terminal alkynes proceeds smoothly and regioselective towards the Markovnikov addition. The addition reaction can be tuned by changing the acidity of the ...