Nanosized Iron-or Copper-Catalyzed Homocoupling of Aryl, Heteroaryl, Benzyl, and Alkenyl Grignard Reagents

…, E Mascaro, F Nador, C Vitale, G Radivoy

Index: Moglie, Yanina; Mascaro, Evangelina; Nador, Fabiana; Vitale, Cristian; Radivoy, Gabriel Synthetic Communications, 2008 , vol. 38, # 22 p. 3861 - 3874

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Citation Number: 16

Abstract

Abstract Under very mild reaction conditions, iron or copper nanoparticles efficiently promoted the homocoupling of different Grignard reagents in tetrahydrofuran at room temperature. The nanosized iron or copper particles were generated in situ in a simple and economical way from commercially available FeCl2 or CuCl2, respectively, an excess of lithium powder, and a catalytic amount (5 mol%) of 4, 4′-di-tert-butylbiphenyl (DTBB) as ...