Development of a panel of immunoassays for monitoring DDT, its metabolites, and analogues in food and environmental matrices

HL Beasley, T Phongkham, MH Daunt…

Index: Beasley, Helen L.; Phongkham, Thipsavanh; Daunt, Margaret H.; Guihot, Simone L.; Skerritt, John H. Journal of Agricultural and Food Chemistry, 1998 , vol. 46, # 8 p. 3339 - 3352

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Citation Number: 43

Abstract

A panel of antisera was prepared using analogues and derivatives of metabolites of the organochlorine insecticide, p, p'-DDT as haptens. The assays developed exhibited differing cross-reactions for different DDT analogues and metabolites, and the choice of hapten for the detecting enzyme conjugate had almost as much effect on assay specificity and sensitivity as the structure of the hapten used for antibody production. Those assays ...