Fluoride ion catalyzed Aldol Reaction between enol silyl ethers and carbonyl compounds

R Noyori, K Yokoyama, J Sakata…

Index: Noyori,R. et al. Journal of the American Chemical Society, 1977 , vol. 99, # 4 p. 1265 - 1267

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Citation Number: 159

Abstract

Under the influence of a catalytic amount (5-10 mol%) of tetrabutylammonium fluoride (TBAF), the enol trimethylsilyl ether 1 reacted with an equimolar amount of benzaldehyde in THF smoothly at low temperatures, giving the aldol silyl ether 2 in> 80% yield. 4 Workup ...