e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Pharmaceutical Chemistry Journal

Synthesis and biological activity of thiazole analogs of isoflavones

VP Khilya, LG Grishko, DV Vikhman

Index: Khilya,V.P. et al. Pharmaceutical Chemistry Journal, 1976 , vol. 10, # 8 p. 1059 - 1062 Khimiko-Farmatsevticheskii Zhurnal, 1976 , vol. 10, # 8 p. 74 - 98

Full Text: HTML

Citation Number: 6

Abstract

Flavonoids are a vast and unusual group of natural compounds interest in which has constantly attracted the attention of many investigators. Flavonoids display significant physiological activity and are nontoxic; consequently they are used widely for medicinal

2-(2,4-dimethyl-1,3-thiazol-5-yl)acetamide Structure

2-(2,4-dimethyl...

~%

1-(2,4-dihydroxyphenyl)-2-(2,4-dimethyl-1,3-thiazol-5-yl)ethanone Structure

1-(2,4-dihydrox...

2-(2,4-dimethyl-1,3-thiazol-5-yl)acetonitrile Structure

2-(2,4-dimethyl...

Resorcine Structure

~%

1-(2,4-dihydroxyphenyl)-2-(2,4-dimethyl-1,3-thiazol-5-yl)ethanone Structure

1-(2,4-dihydrox...

3-(2,4-dimethyl-1,3-thiazol-5-yl)-7-methoxychromen-4-one Structure

3-(2,4-dimethyl...

~%

2-(2,4-dimethyl-1,3-thiazol-5-yl)-1-(2-hydroxy-4-methoxyphenyl)ethanone Structure

2-(2,4-dimethyl...

3-(2,4-dimethyl-1,3-thiazol-5-yl)-7-hydroxychromen-4-one Structure

3-(2,4-dimethyl...

~%

2-(2,4-dimethyl-1,3-thiazol-5-yl)-1-(2-hydroxy-4-methoxyphenyl)ethanone Structure

2-(2,4-dimethyl...

1-(2,4-dihydroxyphenyl)-2-(2,4-dimethyl-1,3-thiazol-5-yl)ethanone Structure

1-(2,4-dihydrox...

~%

2-(2,4-dimethyl-1,3-thiazol-5-yl)-1-(2-hydroxy-4-methoxyphenyl)ethanone Structure

2-(2,4-dimethyl...

2-(2,4-dimethyl-1,3-thiazol-5-yl)acetamide Structure

2-(2,4-dimethyl...

~%

1-(2,4-dihydroxy-6-methylphenyl)-2-(2,4-dimethyl-1,3-thiazol-5-yl)ethanone Structure

1-(2,4-dihydrox...

Orcinol Structure

2-(2,4-dimethyl-1,3-thiazol-5-yl)acetonitrile Structure

2-(2,4-dimethyl...

~%

1-(2,4-dihydroxy-6-methylphenyl)-2-(2,4-dimethyl-1,3-thiazol-5-yl)ethanone Structure

1-(2,4-dihydrox...

2-(2,4-dimethyl-1,3-thiazol-5-yl)acetonitrile Structure

2-(2,4-dimethyl...

~%

3-(2,4-dimethyl-1,3-thiazol-5-yl)-7-hydroxychromen-4-one Structure

3-(2,4-dimethyl...

2-(2,4-dimethyl-1,3-thiazol-5-yl)acetamide Structure

2-(2,4-dimethyl...

~%

3-(2,4-dimethyl-1,3-thiazol-5-yl)-7-hydroxychromen-4-one Structure

3-(2,4-dimethyl...

1-(2,4-dihydroxyphenyl)-2-(2,4-dimethyl-1,3-thiazol-5-yl)ethanone Structure

1-(2,4-dihydrox...

Triethyl orthoformate Structure

Triethyl orthof...

~%

3-(2,4-dimethyl-1,3-thiazol-5-yl)-7-hydroxychromen-4-one Structure

3-(2,4-dimethyl...

1-(2,4-dihydroxyphenyl)-2-(2,4-dimethyl-1,3-thiazol-5-yl)ethanone Structure

1-(2,4-dihydrox...

~%

3-(2,4-dimethyl-1,3-thiazol-5-yl)-7-methoxychromen-4-one Structure

3-(2,4-dimethyl...

2-(2,4-dimethyl-1,3-thiazol-5-yl)acetonitrile Structure

2-(2,4-dimethyl...

~%

3-(2,4-dimethyl-1,3-thiazol-5-yl)-7-methoxychromen-4-one Structure

3-(2,4-dimethyl...

2-(2,4-dimethyl-1,3-thiazol-5-yl)acetamide Structure

2-(2,4-dimethyl...

~%

3-(2,4-dimethyl-1,3-thiazol-5-yl)-7-methoxychromen-4-one Structure

3-(2,4-dimethyl...

3-(2,4-dimethyl-1,3-thiazol-5-yl)-7-hydroxychromen-4-one Structure

3-(2,4-dimethyl...

methyl iodide Structure

~%

3-(2,4-dimethyl-1,3-thiazol-5-yl)-7-methoxychromen-4-one Structure

3-(2,4-dimethyl...

1-(2,4-dihydroxyphenyl)-2-(2,4-dimethyl-1,3-thiazol-5-yl)ethanone Structure

1-(2,4-dihydrox...

~%

[3-(2,4-dimethyl-1,3-thiazol-5-yl)-4-oxochromen-7-yl] acetate Structure

[3-(2,4-dimethy...

2-(2,4-dimethyl-1,3-thiazol-5-yl)acetonitrile Structure

2-(2,4-dimethyl...

~%

[3-(2,4-dimethyl-1,3-thiazol-5-yl)-4-oxochromen-7-yl] acetate Structure

[3-(2,4-dimethy...

2-(2,4-dimethyl-1,3-thiazol-5-yl)acetamide Structure

2-(2,4-dimethyl...

~%

[3-(2,4-dimethyl-1,3-thiazol-5-yl)-4-oxochromen-7-yl] acetate Structure

[3-(2,4-dimethy...

3-(2,4-dimethyl-1,3-thiazol-5-yl)-7-hydroxychromen-4-one Structure

3-(2,4-dimethyl...

Ethanoic anhydride Structure

Ethanoic anhydride

~%

[3-(2,4-dimethyl-1,3-thiazol-5-yl)-4-oxochromen-7-yl] acetate Structure

[3-(2,4-dimethy...