Synthesis of Disubstituted 3-Phenylimidazo [1, 2-a] pyridines via a 2-Aminopyridine/CBrCl3 α-Bromination Shuttle

II Roslan, KH Ng, JE Wu, GK Chuah…

Index: Khan, Abu T.; Ali, Md. Ashif; Goswami, Papori; Choudhury, Lokman H. Journal of Organic Chemistry, 2006 , vol. 71, # 23 p. 8961 - 8963

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Abstract

... All Publications/Website. Select a Journal or Book. ... J. Org. Chem. ... Isolated yields of up to 97% were obtained at 80 °C within 5 h. The 2-aminopyridine/CBrCl 3 system acts as an α-bromination shuttle by transferring Br from CBrCl 3 to the α-carbon of the carbonyl moiety. ...