Mono-and Difunctional Analogs of Some Quinoline and Acridine Nitrogen Mustards1

RM PECK, RK PRESTON…

Index: Peck,R. et al. Journal of Organic Chemistry, 1961 , vol. 26, p. 3409 - 3414

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Citation Number: 25

Abstract

7L'hch pronounced antitumor activity displayed by two eth~ l-2-chloroethylai: iirio: tl~ yla~ iiino derivativte of acridine led to t II (: s\ mthrsis of fiftwn quinoline and acridine analogs of this type for studies of their structrire-activit!. relationships com-I):, irwl\ vit ti t hoscl of th (1 correspoiiding bis (2-chloroethyl) forms. Sisteen other alkylating agents which incorI) or: ttcid a vxripty I,] iiiot1itic: itioiis both iii the si&>(S1i: iin: ind in the qiiinoline or avridine uiirlcws ...