PMR Spectroscopy of Trimethylsilyl Derivatives of Hydroxy Acids

GGS Dutton, N Funnell…

Index: Dutton,G.G. et al. Canadian Journal of Chemistry, 1972 , vol. 50, p. 3913 - 3916

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Citation Number: 3

Abstract

Pmr spectroscopy at 60 MHz of trimethylsilyl ethers and esters, prepared from hydroxy acids, gives well resolved sharp singlets in the range τ 9.8-9.9, These signals may be used to determine the ratio of hydroxyl to carboxyl groups in a molecule. Measurements may be made directly on fractions isolated by gas-liquid chromatography. The influence of the solvent on the resolution is demonstrated.