Copper-catalyzed intermolecular C–H amination of (hetero) arenes via transient unsymmetrical λ3-iodanes

I Sokolovs, D Lubriks, E Suna

Index: Sokolovs, Igors; Lubriks, Dmitrijs; Suna, Edgars Journal of the American Chemical Society, 2014 , vol. 136, # 19 p. 6920 - 6928

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Citation Number: 36

Abstract

A one-pot two-step method for intermolecular C–H amination of electron-rich heteroarenes and arenes has been developed. The approach is based on a room-temperature copper- catalyzed regioselective reaction of the in situ formed unsymmetrical (hetero) aryl-λ3- iodanes with a wide range of primary and secondary aliphatic amines and anilines.

Preparation and reactivity of O 2-sulfonated diazeniumdiolat...

[D'Sa, Raechelle A.; Wang, Yuhong; Ruane, Patrick H.; Showalter, Brett M.; Saavedra, Joseph E.; Davies, Keith M.; Citro, Michael L.; Booth, Melissa N.; Keefer, Larry K.; Toscano, John P. Journal of Organic Chemistry, 2003 , vol. 68, # 2 p. 656 - 657]