e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Benzocycloheptenes and heterocyclic analogues as potential drugs. I. N-Substituted derivatives of 5-amino-6, 7, 8, 9-tetrahydro-5H-benzocycloheptene and …
ZJ Vejdělek, M Protiva
Index: Vejdelek,Z.J.; Protiva,M. Collection of Czechoslovak Chemical Communications, 1971 , vol. 36, p. 1611 - 1623
6, 7, 8, 9-Tetrahydro-5H-benzocyclohepten-5-one (I) was used for the preparation, mostly t'ia 5-amino-6, 7, 8, 9-tetrahydro-5H-benzocycloheptene (XII), of a number of amines and amides (XIII-XXVI). Ketone I reacted with 3-dimethylaminopropylmagnesium chloride to yield the aminoalcohol Vand this was dehydrated to the olefinic amine VI. In connection with attempts to cyclize 2, 5-diphenylvaleric acid (XX V II) some nitrogen derivatives of this acid ...
![9-Phenyl-6,7-dihydro-5H-benzo[7]annulene Structure](https://image.chemsrc.com/caspic/124/21855-89-0.png)
![5-phenyl-6,7,8,9-tetrahydro-5H-benzo[7]annulene Structure](https://image.chemsrc.com/caspic/450/35068-34-9.png)
![2-phenyl-N-(6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-yl)acetamide Structure](https://image.chemsrc.com/caspic/474/35047-55-3.png)
![3,4,5-trimethoxy-N-(6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-yl)benzamide Structure](https://image.chemsrc.com/caspic/436/35047-56-4.png)