e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Liebigs Annalen der Chemie

Dimere Naphthochinone, XVI. Synthese von Maritinon und anderen 8, 8′??Bijuglonen

H Laatsch

Index: Laatsch, Hartmut Liebigs Annalen der Chemie, 1985 , # 12 p. 2420 - 2442

Full Text: HTML

Citation Number: 5

Abstract

Abstract Marition (3a) und die strukturanalogen 8, 8′-Bijuglone 3b und 4b wurden durch Phenoloxidation geeignet substitutierter 2-Brom-1-naphthole erhalten Die Synthese Führt in Nebenreaktionen zu Dinaphthopyranen wie 24, die potentielle Zwischen-und Nebenprodukte der Biosynthese unsymmetrisch 6, 8′-verknüpfter Binaphthochinone sind.

N/A Structure

~92%

8,8'-biplumbagin Structure

8,8'-biplumbagin

N/A Structure

~%

8,8'-biplumbagin Structure

8,8'-biplumbagin

N/A Structure

~%

8,8'-biplumbagin Structure

8,8'-biplumbagin

2-Brom-5,8-dimethoxy-6-methyl-1-naphthol Structure

2-Brom-5,8-dime...

~%

8,8'-biplumbagin Structure

8,8'-biplumbagin

2,2'-Dimethyl-5,5'-dihydroxy-6,6'-bi[1,4-naphthoquinone] Structure

2,2'-Dimethyl-5...

6-Brommaritinon Structure

6-Brommaritinon

Detail

5-Acetoxy-2,3-dichlor-1,4-dimethoxynaphthalin Structure

5-Acetoxy-2,3-d...

~%

5-hydroxy-2,3-dimethoxynaphthalene-1,4-dione Structure

5-hydroxy-2,3-d...

5-acetoxy-2,3-dichloro-[1,4]naphthoquinone Structure

5-acetoxy-2,3-d...

~%

2,3,5-Trihydroxynaphthochinon Structure

2,3,5-Trihydrox...

5-hydroxy-2,3-dimethoxynaphthalene-1,4-dione Structure

5-hydroxy-2,3-d...

5-acetoxy-2,3-dichloro-[1,4]naphthoquinone Structure

5-acetoxy-2,3-d...

~%

2,3,5-Trihydroxynaphthochinon Structure

2,3,5-Trihydrox...

5-hydroxy-2,3-dimethoxynaphthalene-1,4-dione Structure

5-hydroxy-2,3-d...

2-Chloro-3-methoxyjuglone Structure

2-Chloro-3-meth...

2-bromo-5,8-dimethoxy-1-naphthol Structure

2-bromo-5,8-dim...

~5%

2-bromo-5,8-dihydroxynaphthalene-1,4-dione Structure

2-bromo-5,8-dih...

N/A Structure

1,8-Naphthalenediol Structure

1,8-Naphthalenediol

~%

Juglone Structure

N/A Structure

2-Brom-5,8-dimethoxy-6-methyl-1-naphthol Structure

2-Brom-5,8-dime...

~%

2,2'-Dimethyl-5,5'-dihydroxy-6,6'-bi[1,4-naphthoquinone] Structure

2,2'-Dimethyl-5...

Ethanoic anhydride Structure

Ethanoic anhydride

5,5',8,8'-Tetramethoxy-6,6'-dimethyl[2,2'-binaphthyliden]-1,1'-dion Structure

5,5',8,8'-Tetra...

~%

2,2'-Dimethyl-5,5'-dihydroxy-6,6'-bi[1,4-naphthoquinone] Structure

2,2'-Dimethyl-5...

2-Brom-5,8-dimethoxy-6-methyl-1-naphthol Structure

2-Brom-5,8-dime...

~%

8,8'-biplumbagin Structure

8,8'-biplumbagin

2,2'-Dimethyl-5,5'-dihydroxy-6,6'-bi[1,4-naphthoquinone] Structure

2,2'-Dimethyl-5...

6-Brommaritinon Structure

6-Brommaritinon

Detail