T o develop analogues of phenylalkyl isothiocyanate with less toxicity and better biological activity, two water-soluble phenylalkyl isothiocyanate-cysteine conjugates, S-[N-benzyl (thiocarbamoyl)]-cysteine (1) and S-[N-(bphenyl-propyl)(thiocarbamoyl)]-cysteine (2), were synthesized. The induction of increased activity of the detoxifying enzyme glutathione S- transferase by the conjugates and their parent compounds was determined and compared ...
![s-[n-(3-phenylpropyl)(thiocarbamoyl)]-l-cysteine Structure](https://image.chemsrc.com/caspic/366/137915-13-0.png)
![S-[N-BENZYL(THIOCARBAMOYL)]-L-CYSTEINE Structure](https://image.chemsrc.com/caspic/454/35446-36-7.png)