Synthesis

A facile synthesis of 9-(1, 3-dihydroxy-2-propoxymethyl) guanine (Ganciclovir) from guanosine

J Boryski

Index: Synthesis, , # 4 p. 625 - 628

Full Text: HTML

Citation Number: 13

Abstract

... Abstract: The potent and selective antiviral drug ganciclovir (6) has been synthesized in two steps via transpurination of fully acety- lated guanosine (1) in the presence of 1,3-diacetoxy-2-(ace ... 627 Synthesis 1999, No. 4, 625–628 ISSN 0039-7881 © Thieme Stuttgart · New York ...

~71%

A novel approach to the synthesis of the purine anti-viral a...

[Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 42, # 3 p. 651 - 654]

A trihydroxy acyclonucleoside series

[McGee, Danny P. C.; Martin, John C.; Verheyden, Julien P. H. Synthetic Communications, 1988 , vol. 18, # 14 p. 1651 - 1660]

A succinct synthesis of Valganciclovir hydrochloride, a cyto...

[Arkivoc, , vol. 2011, # 2 p. 199 - 208]

A simple and efficient synthesis of 9-substituted guanines. ...

[Alhede; Priess Clausen; Juhl-Christensen; McCluskey; Preikschat Journal of Organic Chemistry, 1991 , vol. 56, # 6 p. 2139 - 2143]

A novel approach to the synthesis of the purine anti-viral a...

[Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 42, # 3 p. 651 - 654]