Tetrahedron letters

A convenient synthesis of unsymmetrical, substituted γ-pyrones from Meldrum's acid

FJ Zawacki, MT Crimmins

Index: Zawacki, Frank J.; Crimmins, Michael T. Tetrahedron Letters, 1996 , vol. 37, # 36 p. 6499 - 6502

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Citation Number: 33

Abstract

A unique approach to the synthesis of mono and disubstituted γ-pyrones from acylated Meldrum's acid and vinyl ethers has been developed. The convenient one pot synthesis of these versatile polyketide equivalents is accomplished without strong base or low temperatures.