Aromatic Enamide/Ene Metathesis toward Substituted Indoles and Its Application to the Synthesis of Indomethacins

Y Kasaya, K Hoshi, Y Terada, A Nishida…

Index: Kasaya, Yayoi; Hoshi, Kosuke; Terada, Yukiyoshi; Nishida, Atsushi; Shuto, Satoshi; Arisawa, Mitsuhiro European Journal of Organic Chemistry, 2009 , # 27 p. 4606 - 4613

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Citation Number: 9

Abstract

Abstract A steric and electronic effect on enamide/ene metathesis, a novel preparation of 2- substituted indoles and 3-substituted indoles using enamide-ene metathesis as a key reaction, and its application to the synthesis of indomethacin are described.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)