Fluorosulfonyl-substituted xanthines as selective irreversible antagonists for the A1-adenosine receptor

AR Beauglehole, SP Baker…

Index: Dhanak, Dashyant; Reese, Colin B. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1986 , p. 2181 - 2186

Full Text: HTML

Citation Number: 19

Abstract

... Journal of ... J. Med. Chem. ... figure Scheme 4 a. a Reagents: (i) K 2 CO 3 , Br(CH 2 ) 3 Phth, DMF; (ii) method A − MeNH 2 , MeOH, method B − NH 2 NH 2 ·H 2 O; (iii) HO 2 CC 6 H 4 SO 2 F, EDCI, DIPEA; (iv) Br(CH 2 ) 3 NHC(O)C 6 H 4 SO 2 F, K 2 CO 3 , DMF; (v) aq HCl. figure ...