European Journal of Organic Chemistry 2018-02-20

Cover Feature: Pre-Activation-Based Stereoselective Glycosylations (Eur. J. Org. Chem. /2018)

Bo Yang, Weizhun Yang, Sherif Ramadan, Xuefei Huang

Index: 10.1002/ejoc.201800274

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Abstract

The Cover Feature shows that pre-activation-based glycosylation separates donor activation and acceptor glycosylation into two distinct steps. As a result, unique stereochemical control can be achieved by judicious choices of protective groups, anomeric groups, additives, and solvents. Some highly challenging glycosyl linkages including β-mannosides and deoxy glycosides can now be prepared with high stereoselectivities. More information can be found in the Microreview by X. Huang et al.