Metal-and Oxidant-Free Synthesis of Quinazolinones from β-Ketoesters with o-Aminobenzamides via Phosphorous Acid-Catalyzed Cyclocondensation and Selective …

Z Li, J Dong, X Chen, Q Li, Y Zhou…

Index: Zhan, Dan; Li, Tianbin; Wei, Haidong; Weng, Wen; Ghandi, Khashayar; Zeng, Qingle RSC Advances, 2013 , vol. 3, # 24 p. 9325 - 9329

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Citation Number: 13

Abstract

A general and efficient phosphorous acid-catalyzed cyclocondensation of β-ketoesters with o-aminobenzamides via selective C–C bond cleavage leading to quinazolinones is developed. This reaction proceeds smoothly under metal-and oxidant-free conditions, giving