Tetrahedron letters

Synthesis of isogranulatimide analogues possessing a pyrrole moiety instead of an imidazole heterocycle

B Hugon, B Pfeiffer, P Renard, M Prudhomme

Index: Hugon, Bernadette; Pfeiffer, Bruno; Renard, Pierre; Prudhomme, Michelle Tetrahedron Letters, 2003 , vol. 44, # 20 p. 3927 - 3930

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Citation Number: 34

Abstract

An efficient four step synthesis from commercial indoles of isogranulatimide analogues is reported. In the new compounds, the imidazole moiety is replaced by a pyrrole unit, the indole part is substituted or not in 5-position and the nitrogen of the imide moiety bears or not a methyl substituent.