Tetrahedron Letters

4-(Dimethylamino) pyridine as a catalyst for the lactonization of 4-hydroxy-2-methylenebutanoate esters

DR Nicponski

Index: Nicponski, Daniel R. Tetrahedron Letters, 2014 , vol. 55, # 13 p. 2075 - 2077

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Citation Number: 4

Abstract

Abstract The catalytic action of 4-(dimethylamino) pyridine (DMAP) in lactonizing 4-hydroxy- 2-methylenebutanoate esters to 2-methylene-γ-butyrolactones is described. The use of DMAP, which functions as an excellent complement to the more traditional acid-catalyzed