Synthesis

One-pot synthesis of 3-substituted isoxazoles from phenyl vinylic selenide

SR Sheng, XL Liu, Q Xu, CS Song

Index: Sheng, Shou-Ri; Liu, Xiao-Ling; Xu, Qu; Song, Cai-Sheng Synthesis, 2003 , # 18 p. 2763 - 2764

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Citation Number: 18

Abstract

1,3-Dipolar cycloaddition of nitrile oxides with acetylenes is a useful procedure for the introduction of isoxazoles, which are important class of heterocycles used as intermediates for natural product synthesis and building blocks for construction of new molecular systems. [1] Although methods for the synthesis of isoxazoles are well documented, [2] efforts are continuing for the development of more efficient methods with experimental simplicity. To the best of our knowledge, all ...