Pd??Catalyzed Asymmetric Synthesis of N??Allenyl Amides and Their Au??Catalyzed Cycloisomerizative Hydroalkylation: A New Route Toward Enantioenriched …

A Boutier, C Kammerer??Pentier…

Index: Boutier, Audrey; Kammerer-Pentier, Claire; Krause, Norbert; Prestat, Guillaume; Poli, Giovanni Chemistry - A European Journal, 2012 , vol. 18, # 13 p. 3840 - 3844

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Citation Number: 26

Abstract

Over the past decade, much attention has been devoted to gold catalysis for the synthesis of heterocycles through carbon–carbon and carbon–heteroatom bond formation.[1] Indeed, AuI and AuIII complexes are carbophilic Lewis acids that are able to activate unsaturated carbon– carbon bonds towards nucleophilic attack. However, gold-catalyzed hydroalkylations involving an activated methylene function have only been rarely studied,[2] and, to the ...