Tetrahedron letters

2-Nitrofurans as dienophiles in Diels–Alder reactions

C Della Rosa, MN Kneeteman, PME Mancini

Index: Rosa, Claudia Della; Kneeteman, Maria N.; Mancini, Pedro M.E. Tetrahedron Letters, 2005 , vol. 46, # 50 p. 8711 - 8714

Full Text: HTML

Citation Number: 35

Abstract

It has been known for some time that aromatic heterocycles, such as furan, thiophene and pyrrole undergo Diels–Alder (DA) reactions despite their aromaticity and hence expected inertness. In view of their electron-rich constitution and electron-donor properties, they have been mostly involved as the diene component in the cycloaddition process. 1 However, there exists a limited number of examples of five-membered, aromatic heterocycles acting as dienophiles in ...