Iron (II)-catalyzed benzylic fluorination

S Bloom, CR Pitts, R Woltornist, A Griswold…

Index: Takeda, Youhei; Hayakawa, Junpei; Yano, Kazuki; Minakata, Satoshi Chemistry Letters, 2012 , vol. 41, # 12 p. 1672 - 1674

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Citation Number: 73

Abstract

... drug discovery, a mild benzylic fluorination method may prove itself a useful instrument for the medicinal chemist (eg, potentially ... Clearly, iron is crucial in reaction selectivity favoring the benzylic position over chemistry at the more acidic α-carbon. ... (American Chemical Society). A ...