e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Reaction of quinoxaline derivatives with nucleophilic reagents.
…, HAH El-Sherief, AES Abdel-Rahman, MF Aly
Index: Badr, Mahmoud Zarif Amin; El-Naggar, Galal Mohamed; El-Sherief, Hassan Ahmad Hassan; Abdel-Rahman, Abdou El-Sayed; Aly, Moustafa Fouzy Bulletin of the Chemical Society of Japan, 1983 , vol. 56, # 1 p. 326 - 330
2-Chloro-3-methylquinoxaline reacts with aromatic amines in basic medium forming 2- arylamino-3-methylquinoxalines, also it reacts with mercaptoacetic acid. The 3-methyl-2 (1H)-quinoxalinone condenses with aromatic aldehydes forming the corresponding 3- (substituted styryl)-2 (1H)-quinoxalinones which add bromine in acetic acid to yield the corresponding dibromo derivatives which react with morpholine, sodium methoxide, and ...