Synlett

Regioselective and versatile synthesis of indoles via intramolecular Friedel-Crafts heteroannulation of enaminones

M del Carmen Cruz, F Jimenez, F Delgado, J Tamariz

Index: Synlett, , # 5 p. 749 - 755

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Citation Number: 14

Abstract

... Synlett 2006(5 ... 5j: a) i) DMFDMA, 90 °C, 5 h; ii) AlCl 3 , CH 3 CN, 20 °C, 24 h. For indoles 5k-m: a) i) DMFDMA, 90 °C, 5 h; ii ... 5i-m (Scheme [4] ). Thus, when a mixture of the respective compound 7j or 7k and DMFDMA (1.1 mol equiv) was heated to 90 °C for five hours, followed by ...