Tetrahedron Letters

Ligand-free copper (Ι)-catalyzed Sonogashira-type coupling of arylboronic acids with terminal alkynes

C Pan, F Luo, W Wang, Z Ye, J Cheng

Index: Pan, Changduo; Luo, Fang; Wang, Wenhui; Ye, Zhishi; Cheng, Jiang Tetrahedron Letters, 2009 , vol. 50, # 35 p. 5044 - 5046

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Citation Number: 33

Abstract

An efficient ligand-free CuI-catalyzed Sonogashira-type coupling reaction of arylboronic acids with terminal alkynes under air is described. The electron-deficient alkynes gave the desired cross-coupling products in good yields. Thus, it represents a simple and alternative method for the traditional Sonogashira reaction.