Nine new macrocyclic hosts have been designed, synthesized, and examined for their ability to bind alkali metal, ammonium, and alkylammonium cations. Their ring sizes vary from 17-to 24-membered. Five contain axially chiral units, three of which have not previously been incorporated in a host. Their structures are indicated by line formulas in which sequences of letters indicate the units and their points of attachment through which they are ...