Synlett

Iron-Catalyzed Benzylation Reaction of Arenes with Benzyl Thiocyanates

…, DY Zhao, JH Li, XG Zhang, CL Deng, RY Tang

Index: Guo, Xiao-Kang; Zhao, Dong-Yun; Li, Jin-Heng; Zhang, Xing-Guo; Deng, Chen-Liang; Tang, Ri-Yuan Synlett, 2012 , # 4 p. 627 - 631

Full Text: HTML

Citation Number: 6

Abstract

Abstract A novel, regioselective protocol for the synthesis of diphenylmethane derivatives has been developed by using iron-catalyzed Friedel-Crafts reaction of arenes with benzyl thiocyanates. In the presence of FeBr 3, a variety of benzyl thiocyanates underwent the reaction with arenes to selectively afford the corresponding diarylmethane derivatives in moderate to high yields.

~69%

~97%

~77%

~76%

~56%

Multimetallic Ir–Sn 3-catalyzed substitution reaction of π-a...

[Maity, Arnab Kumar; Chatterjee, Paresh Nath; Roy, Sujit Tetrahedron, 2013 , vol. 69, # 2 p. 942 - 956]

Intermolecular Friedel–Crafts reaction catalyzed by InCl 3

[Kaneko, Miho; Hayashi, Ryuji; Cook, Gregory R. Tetrahedron Letters, 2007 , vol. 48, # 40 p. 7085 - 7087]

InBr3??Catalyzed Deoxygenation of Carboxylic Acids with a Hy...

[Sakai, Norio; Kawana, Keita; Ikeda, Reiko; Nakaike, Yumi; Konakahara, Takeo European Journal of Organic Chemistry, 2011 , # 17 p. 3178 - 3183]

A simple preparation of diarylmethanes by oxidative friedel-...

[Kobayashi, Tomoshige; Rahman, Sheikh Maksudur Synthetic Communications, 2003 , vol. 33, # 22 p. 3997 - 4003]

The synthetic potential of graphite-catalyzed alkylation

[Sereda, Grigoriy A.; Rajpara, Vikul B.; Slaba, Ryan L. Tetrahedron, 2007 , vol. 63, # 34 p. 8351 - 8357]